THC Vs. CBD: Know The Actual Difference Before You Start

January 11, 2022 4 min read

Molecular structural Difference between THC and CBD - Enveed

THC Vs. CBD: Know The Actual Difference Before You Start

Consumers are increasingly interested in their options as hemp, and other cannabis products become legal. Cannabidiol (CBD) and tetrahydrocannabinol (THC), two different chemicals found in Cannabis plants, are examples.

Hemp or cannabis can be used to extract CBD.

Cannabis sativa is the plant that produces hemp and cannabis. THC levels in legal hemp must be less than 0.3 percent. CBD can be found in various forms, including gels, gummies, oils, capsules, extracts, and more.

THC (tetrahydrocannabinol) is the psychoactive component in cannabis that causes a high feeling. It is possible to consume it by smoking cannabis. Oils, foods, tinctures, pills, and other forms are also available.

Both substances interact with the endocannabinoid system in your body, but their effects are vastly different.

Continue reading to learn about these substances. While they have a great deal in common, a few essential variances influence how they're employed.

THC vs CBD - Enveed

THC Vs. CBD: Chemical Structure

CBD and THC have the same molecular structure: 21 carbon atoms and 30 hydrogen atoms, and two oxygen atoms. The different impacts on your body are due to a minor change in how atoms are organized.

CBD and THC are chemically identical to the endocannabinoids found in your body. They'll be able to engage with your endocannabinoid system due to this.

The production of neurotransmitters in the brain is affected by the connection. Neurotransmitters are substances that convey messages among cells and play a part in various functions, including pain, immunological function, stress, & sleep, to mention a few.

THC vs. CBD: Psychoactive Ingredients

THC vs CBD - Enveed

CBD and THC have different psychotropic effects despite their comparable chemical makeup. CBD has a psychoactive effect, but not the same way as THC does. It does not create the same high as THC. CBD has been demonstrated to aid in treating anxiety, sadness, and seizures.

THC binds to the brain's cannabinoid 1 (CB1) receptors. It gives you a high or a feeling of euphoria.

CBD binds to CB1 receptors very poorly, if at all. CBD requires THC to connect to the CB1 receptor, which can help minimize some of THC's undesirable psychotropic effects like euphoria and sedation.

THC vs. CBD: Legality

State Regulated Cannabis Programs - Enveed

Cannabis-related legislation in the U. S. is constantly changing. CBD is still classified as a Schedule I substance under federal law.

Although hemp has indeed been removed from the Controlled Substances Act, CBD is still classified as a Schedule I substance by the Drug Enforcement Administration (DEA) and the Food and Drug Administration (FDA).

However, 33 states and the District of Columbia have passed cannabis-related legislation, enabling medical cannabis with higher THC levels lawful. A licensed physician may be required to prescribe cannabis.

In addition, numerous states have legalized the use of cannabis and THC for recreational purposes.

CBD should be available in states wherever cannabis is allowed for medical and recreational use.

It's crucial to check your state's legislation before acquiring CBD or THC products.

You could face legal consequences if you have cannabis-related items in a state where they're banned or if you don't have a valid prescription in states in which the products are authorized for medicinal treatment.

THC vs. CBD: Medical Advantages

The medical benefits between THC and CBD - Enveed

Many of the medical benefits of CBD and THC are the same. They could provide relief from a number of the same ailments. On the other hand, CBD does not produce the same euphoric effects as THC. Because of the absence of this adverse effect, some individuals may prefer to utilize CBD.

The FDA authorized True Source Epidiolex, the first CBD-based prescription drug, in June 2018. It's used to treat epilepsy that's unusual and difficult to manage. (Any of the other criteria mentioned below are not approved for Epidiolex.)

CBD is used to help with other various conditions, such as:

  • Seizures
  • pain
  • inflammation
  • anxiety
  • psychosis or mental disorders
  • migraine
  • inflammatory bowel disease
  • nausea
  • depression


THC is used to help with the following:

  • Pain
  • insomnia
  • muscle spasticity
  • glaucoma
  • anxiety
  • low appetite
  • nausea


THC vs. CBD: What Are the Consequences?

Even in high doses, CBD is well tolerated. Any CBD-related adverse effects, according to ResearchTrusted Source, are most likely a result of drug-to-drug contacts between CBD as well as other medication you may well be taking.

The euphoric characteristics of the chemical cause these adverse effects.

On the other hand, high THC consumption may be linked to long-term detrimental psychological effects. This is particularly true for teenagers who use substantial amounts of THC, even though there is no solid proof that cannabis causes psychiatric diseases like schizophrenia.

THC Vs. CBD: Drug Testing

How to avoid Positive CBD Drug Test - Enveed

CBD and Thc are cannabinoids that are retained in the body's fat. They can appear on doping tests for days or even weeks after you've used them.

CBD-sensitive tests are available, but not all drug tests will detect CBD. THC use may show up on screening because most conventional drug tests check for compounds related to THC.

Hemp can also create THC in addition to CBD, which is why a test for THC could come up positive even if you haven't used it.



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In the United States, the Food and Drug Administration (FDA) has no authority to regulate Cannabidiol oil products, and the substance may be illegal in some states.

Consider consulting with a doctor prior to using Cannabis products and verifying that any goods you use are from reliable sources before using.